Real Security of result
with the COBAS INTEGRA® clot detection system

Highly sensitive pressure sensors detect incorrect pipetting,
even at 2 µl sample volume.
Handling of clotted samples is improved with immediate
flagging of faulty samples.
System wash pressures have been optimised to fully remove
the clot from the sample probes, avoiding any maintenance
actions and interruptions to workflow.
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INTEGRA reagent cassettes
make reagent preparation a task of the past

Patented cassette design plus on-board refrigeration
prevents reagent evaporation and degradation, ensuring
long-term on-board stability and long calibration intervals.
Each cassette holds all necessary reagents for up to
800 determinations, maximising on-board capacity and reducing
the possibility of errors and saving staff time.
Reagent preparation is a task of the past. The barcoded
reagent cassettes are automatically handled by the system,
reducing the possibility of errors an saving time.
Compact cassette design means that more than a year's
supply of tests for a typical laboratory can easily be
stored in a single refrigerator.
Workflow consolidation
with the choice of over 140 applications
More than 140 applications for all types of sample matrices
are measured with one of 4 different measuring technologies
- absorbance photometry, turbidimetry, fluorescence polarisation
and ion selective potentiometry.
The COBAS INTEGRA® 400
plus system has up to 36 different onboard assays.
For quick access to additional tests, cassette racks can
be exchanged while the system is running. Offboard storage
of pre-calibrated cassettes allows full flexibility.
The broad menu includes clinical chemistry, specific
proteins therapeutic drug monitoring, drug of abuse testing
and much more. Consolidation on a single system improves
turnaround times by reducing the need for sample splitting.
Onboard storage of 32 cassettes at 12°C ensures reagent
stability up to 3 months, reducing reagent wastage and
costs.
For high volume tests, multiple cassettes of the same
assay can be on-board for automatic switch-over during
run.
Sophisticated software programms
to simplify operation and training

On-screen inventory management tracks reagents available
on-board and forecasts if additional cassettes are required
based on daily workload statistics.
The intelligent processing on COBAS INTEGRA® 400
plus automatically schedules each sample's tests
to minimise analyser turnaround time and increase throughput,
while allowing immediate STAT testing 24 hours a day.
Quality control programs monitor precision and accuracy
to ensure reliable results.
Validated sample results are continuously transmitted
to the LIS via the host query communication mode, guaranteeing
fast result availability.
The software automatically tracks service needs and alerts
the user when maintenance is due. Activities are recorded
in the electronic log to support compliance with Good
Laboratory Practice and Accreditation.
Remote diagnostics by modem allows Roche service personnel
to resolve errors quickly and efficiently without an on-site
visit.
Reduced costs through increased
efficiency
Consolidation eliminates pre-analytical phase tasks by
reducing sample splitting to improve workflow and decrease
handling costs.
Long on-board reagent stability and fewer calibrations
mean less waste and lower cost per reportable result.
A single workstation optimises use of time and budget
by reducing costs of operating, maintaining and servicing
multiple analytical systems.
Processing time can be reduced by up to 50% compared
with dedicated analysers.
Post-analytical tasks such as sample tracking, rerunning,
archiving and disposal are greatly simplified by use of
a single consolidated system - COBAS INTEGRA® 400
plus.
Continuous sample
access
to up to 90 samples for a smoother workflow

Sample racks allow continuous access as tests are completed
and new samples arrive, eliminating unnecessary test delays.
Up to 90 barcoded samples, in six 15 position racks,
can be loaded onboard. STATs are automatically given priority
and immediately processed once the barcode is read to
speed up delivery of results to the physician.
Serum, plasma, urine, hemolysate, whole blood and CSF
can be used in barcoded primary or secondary tubes. Microcups
can be used for low volume samples, e.g. paediatric and
CSF.
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